Type O Negative was so creatively dominated by Peter Steele that the content and tone of their albums was highly dependent on his moods. This, for instance, is why their debut (Slow, Deep and Hard) is so incredibly angry - Peter was a very angry man at that point - whilst World Coming Down was such a downer even by their usual standards. Dead Again came out in 2007, a time when Steele claimed to have turned his life around - to the point where he claimed ot have found religion in some interviews - and you can sort of tell because there's a perkiness to the compositions which is absent from much earlier Type O material.
It isn't a radical departure from their sound, but it's less emotionally committed to their classic downer approach than any preceding album, with the end result being that the album feels a little insincere and generic. It's an OK listen if you're into Type O, but I'd recommend anything between Bloody Kisses and Life Is Killing Me over this.